Medications containing codeine

Codein is used along or as one of the components in some medicines.
Codein systemic is indicated to treat cough, pain, and is applied as antidiarrhoeal medicine.
Some multi-component medications contain codeine. They are used to treat headaches, relieve pain, treat upper respiratory symptoms, hay fever, cold symptoms, nasal congestion, osteoarthritis, muscle spasms, rhinorrhea, allergies and sinus symptoms.
The following are the examples of such multi-component medicines with codeine:
•    acetaminophen/aspirin/codeine systemic;
•    acetaminophen/butalbital/caffeine/codeine systemic;
•    acetaminophen/chlorpheniramine/codeine systemic;
•    acetaminophen/chlorpheniramine/codeine/phenylphrine systemic;
•    aspirin/butalbital/caffeine/codeine systemic;
•    bromodiphenhydramine/codeine systemic;
•    brompheniramine/codeine/phenylpropanolamine systemic;
•    chlorcyclizine/codeine systemic;
•    chlorcyclizine/codeine/phenylephrine systemic;
•    chlorpheniramine/codeine/phenylephrine/phenylpropanolamine systemic;
•    chlorpheniramine/codeine/phenylephrine/potassium iodide systemic;
•    codeine/guaifenesin systemic;
•    codeine/guaifenesin/phenylpropanolamine systemic;
•    codeine/pheniramine/phenylephrine/sodium citrate systemic;
•    others.
The use of any medicine containing codeine should be carefully considered by a medical professional with regard of possible allergic reactions to codeine, possible tolerance, psychologic and/or physical dependence.

Side effects of Codeine


Visit a doctor at once  if you have the next allergic reaction  to codeine:; swelling of your  throat, face, tongue, lips; difficulty breathing; hives;
Also call your doctor at once  if a child taking Codeine has:  sighing, noisy slow breathing with long pauses between breaths; breathing,being unusually hard to wake up and sleepy; blue colored lips.

The serious side effects to Codeine may include:

  •  weak pulse,  shallow breathing;
  •  fainting,  slow heart rate;
  •  unusual thoughts or unusual  behavior;
  •  confusion, hallucinations,  agitation;
  •  feeling like you might pass out;
  •  feelings of sadness or extreme happiness ;
  •  problems with urination;
  •  seizure (convulsions).

Less serious side effects include:

  •  drowsy;
  •  feeling dizzy; or
  •  nausea, stomach pain;
  •  mild itching or.
  •  mild  rash;
  •  constipation;
  •  vomiting;
  •  sweating.

 

Before taking

If you want to start use Codeine, consult with your health care professional. You doctor must know if you have the next condition:

  •  -COPD, asthma, sleep apnea, or other
  •  -underactive thyroid;
  •  - liver disease
  •  -kidney disease;
  •  -a history of  brain tumor;
  •  -curvature of the spine;
  •  -seizure disorder;
  •  -a history of head injury or
  •  -low blood pressure;
  •  -a pancreas disorder;
  •  -gallbladder disease;
  • - an intestinal disorder;
  • -  urination problems, enlarged prostate
  • -  adrenal gland disorders,  Addison’s disease;
  • -  mental illness; or
  • -  a history of drug addiction.
  • - a history of alcohol addiction

Use of сodeine by nursing mothers

Expert have  different points of view concerning Codeine admission by nursing mothers. Codeine turns into morphine in the human body. Some experts believe that breastfeeding women metabolism substances may be accelerated. Such a reaction can potentially be life threatening to the baby.

The experts from Institute for Clinical Evaluative Sciences in Toronto believe that taking codeine by mother is safe for the baby. Researchers for ten years saw 7804 children, mothers who took codeine after childbirth. They also observed a control group of women who gave birth at the same time. However, long-term observations did not reveal any abnormalities, caused by taking codeine.

However, researchers acknowledge that in terms of interaction with various drugs and converting codeine into morphine the effects are unpredictable. Earlier studies of Australian anesthetist Gavin Pattullo shows that mother drowsiness caused by taking codeine may be an alarming signal.

Codeine overdose

Codeine is a drug belonging to the class of opiates. Codeine can be used orally, subcutaneously, intramuscularly and rectally. Codeine cannot be safely administered intravenously as a solution for injection, as this may lead to pulmonary edema and face swelling. Besides, it cannot be used intranasally (through the nose).

Codeine overdose symptoms:

  • Slow and labored breathing
  •  Shallow breath
  •  Loss of breath
  •  Bluish color of nails and lips
  •  Itching
  • Stomach cramps and / or intestinal tract spasms
  • Сonstipation
  • Weak pulse
  • Low blood pressure

 

Codeine history

Codeine is a derivative of opium – opiates. These drugs were known in ancient Egypt. In those days, and later opium was used as a relaxing and pain-relieving agent. There are some facts that thousand years before our era, in the Mediterranean, the doctors used poppy derivatives to treat humans. In the East, these substances have appeared thanks to Alexander the Great. These drugs were very widely used during military campaigns. Soldiers used them to strengthen their fighting qualities.

In the sixteenth century some opiate drugs were recognized by official medicine. Doctor Paracelsus wrote about opiates in his works. First information about negative effects of these substances appeared only in the eighteenth century, but in spite of this, in certain segments of the population, they are used almost without exception.

Codeine relieves pain of any type. Codeine, affect the human psyche in such a way that the person forget all the problems, becomes “good and peaceful.” Codeine suspends the activity of brain regions responsible for breathing and coughing. Codeine has a big effect on muscles of the intestine. Effect is manifested in difficulties with defecation. If you use codeine during a long period, the effect is reduced, the body gets used. If you stop using codeine suddenly, then the state of withdrawal arrives. If we consider the effects on people of all existing drugs, the opiates are the most dangerous.

How to take codeine?

Codeine is one of the few opiates which are taken orally. Codeine mostly comes in tablet form. Some oral medications containing codeine also contain small amounts of caffeine to counteract the sedative effects of codeine. When taking codeine tablets, pain relief can last from 3 to 6 hours.

Besides, codeine is a component of cough syrups. These syrups also contain expectorants to clear the airways of mucus. Cough medicines containing codeine are taken every 4 hours. The usual dose is 1 tablespoon with a glass of water.

The doctor recommend:

If you take Codeine for the first time start out with 60mg then after 45 min or so if you don’t feel as you wish take some more.

Codeine: general information

Medical uses

Codeine is a narcotic substance that is derived from opium. Its action is similar to morphine, but slightly weaker. It is used as antitussive and analgesic.

Codeine also have antidiarrheal, antianxiety, antihypertensive,anesthetic, sedative and hypnotic properties. Although as anesthetic, codeine is used rarely, because the effect of codeine is weaker.

Preparations

Solution: 15 mg/5ml (teaspoon). Tablets: 15, 30, 60 mg. Injection: 15 and 30 mg/ml.

How to take

The dosage is prescribed by the doctor. The usual adult dose is 15-60 mg every 4-6 hours.

Precautions

During pregnancy and lactation you have to consult with your doctor. Codeine is not used with alcohol and you must be careful when driving. Also may be habit-forming, so should be used only for intended purposes. Not be used in asthma and bowel obstruction.

Side effects

Drowsiness and constipation, itching, nausea, vomiting, depression, dry mouth, urinary retention, miosis, orthostatic hypotension and even death. There can be an allergic reaction in the form of the swelling of skin and rashes.

If you feel dizzy, cold clammy sweat, drowsiness, anxiety, reduction in blood pressure, severe weakness, if you breath hard you must inform your doctor.Storage conditions

Codeine should be stored in dry place at 15 – 30 C, away from direct heat and light. Keep out of the reach and sight of children.